Chemistry

Recent neutron experiments have unveiled critical insights into the enzymatic mechanisms that play a pivotal role in cancer metabolism. Conducted at the Department of Energy’s Oak Ridge National Laboratory (ORNL), these studies spotlight serine hydroxymethyltransferase (SHMT), an enzyme crucial for cell division. Utilizing neutron diffraction techniques at the Spallation Neutron Source and the High Flux
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As the global push towards sustainable energy sources intensifies, hydrogen gas emerges as a frontrunner for a greener future. Renowned for its high energy density and environmentally friendly profile—producing only water when burned—hydrogen offers a sustainable solution to today’s pressing energy challenges. Despite its abundance in the universe, primarily as part of chemical compounds like
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As global populations grow and urbanization accelerates, the demand for safe, clean water becomes more critical than ever. Traditional wastewater treatment systems are often ill-equipped to handle the complex array of contaminants present in municipal effluents, particularly pharmaceutical micropollutants. Studies reveal that as many as 4,000 different pharmaceuticals can be found in our water systems,
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The recent awarding of the Nobel Prize in Chemistry has marked a significant milestone in the field of molecular biology, spotlighting groundbreaking work on proteins, the essential components of life. The distinction was granted to three trailblazing scientists: Demis Hassabis and John Jumper from Google’s DeepMind lab, along with the biochemist David Baker. Their combined
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Covalent bonds are fundamental to the structure of organic compounds, enabling atoms to interconnect by sharing electrons. Traditionally, these bonds involve pairs of electrons and are crucial in forming stable molecular structures. Linus Pauling, a luminary in chemistry, posited in 1931 that single-electron covalent bonds—bonds formed by only one unpaired electron—might exist. However, he cautioned
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In a remarkable advancement for organic chemistry, researchers at Hokkaido University, Japan, have unveiled a groundbreaking method for activating alkanes, which have long been seen as challenging, yet crucial components in the chemical industry. The publishing of their research in the prestigious journal *Science* marks a transformative leap in how these prevalent compounds can be
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Biofilms, composed of clusters of microorganisms including bacteria and fungi, form protective layers on various surfaces—be it medical devices, human tissue, or industrial pipes. These dense congregations create a significant hurdle in medical treatments, particularly for chronic wounds where antibiotic treatments often fall short. The organisms within biofilms are typically in a dormant state, rendering
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Industrial processes are integral to modern economies, yet they often come at a significant environmental cost. Among the numerous pollutants generated, nitrogen oxides (NOx)—a collective term encompassing nitric oxide (NO) and nitrous oxide (N2O)—stand out due to their detrimental effects on both human health and the environment. Nitric oxide is notorious for contributing to respiratory
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Plastic pollution presents an ever-growing challenge for the environment, with statistics demonstrating its alarming reach. Each year, the world produces over 368 million metric tons of plastics, out of which a staggering 13 million metric tons find their way into soils and ecosystems. This plastic which pervades both land and sea poses significant threats to
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The pharmaceutical industry has long grappled with the challenges posed by the enantiomers of organic compounds—molecules that are mirror images of one another. While these enantiomers, or “mirror molecules,” possess the same chemical properties, their activities within biological systems can diverge significantly. This divergence has profound implications for drug efficacy and safety, with one enantiomer
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Recent findings from a research team led by Professor Jaeheung Cho at UNIST shed light on the intricate interplay between cobalt(III)-based metal complexes and nitrile substrates. Highlighted in the Journal of the American Chemical Society, this research delves into the reaction mechanisms employed by cobalt(III) within biomimetic frameworks. The significance of metal spin states emerges
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Recent advancements from the National University of Singapore (NUS) have led to a paradigm shift in the realm of asymmetric catalysis, prominently through the innovative use of chiral deoxyribonucleic acid (DNA) catalysts. Traditionally, enzyme catalysis—a method that capitalizes on the inherent qualities of biological proteins—has been a cornerstone for synthesizing chiral molecules. Nevertheless, proteins often
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The electrochemical reduction of carbon dioxide (CO2) has emerged as a frontier in sustainable chemistry, steering a conversation about turning a notorious greenhouse gas into valuable products. Traditionally, the focus has been on perfecting the catalysts used in these reactions, with scientists investing considerable effort into enhancing their efficiency and selectivity. However, recent research has
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